The car Senna debuted in, the Toleman TG184, will be on display, as well as the Lotus 97T, which powered Senna to a maiden grand prix victory in Portugal in 1985.
Local fans will also be able to see world champion Emerson Fittipaldi and Felipe Massa in action.
"The opportunity of seeing, so close, historical cars, that were part of some of his best moments in F1, will be incredible.
"Having the chance to see an event with so many attractions, happening in Ibirapuera, the heart of Sao Paulo, will be even more remarkable, crowning 2019, a year full of beautiful tributes to celebrate 25 years of legacy."
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