Up to 15 personnel are believed to be switching allegiance, with 20-year Mercedes veteran Ben Hodgkinson the most high-profile name departing to date as he takes on the role of technical director of Red Bull Powertrains.
Insisting he is not distracted by off-track affairs, Hamilton said: "It is not something I put any energy towards.
"There is, obviously, all this that is going on in the background. I think I have the best ally in Toto [Wolff] who will be working to manage it in the best way possible.
"Without a doubt, every individual in our team is amazing and it is not a surprise that everybody will want them.
"We have had a lot of success together. If there are people who have gone, I wish them all the best, we all have to go through our own journeys and make our own decisions which are right for us."
Mercedes has won every title available since the introduction of turbo-hybrid engines in 2014 with the powertrain the major factor in the early years of its domination.
Hamilton added: "This is a huge team. It is not about one individual or even five, it is about one collection and an amazing collection of people that remains solid and focused on winning this championship."
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