Asked if he had dared to dream of victory, Perez said: "Yeah, I've dreamt a few times already about it.
"It will be massive for me. Obviously, that's the target for Sunday [but] but will not be easy. We need to be perfect throughout the weekend.
"So all the focus will be now on the racing stuff, to try to maximise a weekend.
"At the end of the day, it's another weekend with the same amount of points but it's the most special one for me."
Mexico F1 contract extension "great for our country"
The Mexico City Grand Prix was set to be out of contract at the end of the year, but after already being included on the calendar for 2023, a formal extension for another three years was announced on Thursday.
"This is something great for our country, because this country, we get to show how good that Mexicans are, our Mexican people, our country," added Perez.
"Formula 1 gives you that exposure worldwide, so I'm super proud of my country, that we are able to secure another contract with Formula 1. Super-happy for that."